1. Rodriguez RNG, et al. Moreover, patients with coconut allergy present cross-reactivity to walnuts, with 11S the shared allergen (Teuber & Peterson, 1999). Question Posted 8/14/2012: Zurich: European Academy of Allergy and Clinical Immunology, 166-167. Both the skin and fruit of papaya contain an enzyme similar to latex that can trigger an allergic reaction in some individuals. The only true test of allergy to a food, especially when we do not have negative and positive predictive value for in vitro tests, is an oral challenge. However, this cross-reactivity did not extend to mango pulp, although it was present in mango seed (4). This clearly applies to potential cross-reactivity to pistachio and cashew in a patient with mango allergy. Mango cross-reactivity with cashew and pistachio (Poster: XXI Congress of EAACI). 2. This is also the similar compound present in avocadoes and bananas. For example, there is a fruit profilin in mango which is also found in pear, peach, and apple. Taking all of these data and reports into consideration, one can draw the following conclusions: Thank you again for your inquiry and we hope this response is helpful to you. Systemic contact dermatitis to raw cashew nuts in a pesto sauce. References: IgE-mediated allergic reaction to mango: What is the incidence of that reaction? In: Akdis, C A; Agache, I. EAACI Global Atlas of Allergy. This site uses cookies. Plants with allergens that potentially cross-react with poison ivy and other Toxicodendrons, and the concepts of systemic contact dermatitis and hyposensitization are reviewed. Thus, based upon in vitro studies, there has been surprisingly little cross-reactivity demonstrated between mango pulp and pistachio and cashew. Some fruits, vegetables, nuts, and grains can cause cross reactions with latex. Papain allergy: Papaya contains papain. Clin Exp Allergy 1995; 25(12):1254-1259. While we are reporting the first case of jackfruit anaphylaxis, further research needs to be conducted to identify the mechanisms underlying it. However, such cross-reactivity probably occurs less frequently than predicted by the biological taxonomy of these foods (3). In vitro allergy diagnosis – allergen-specific IgE. Reviewed: 5/8/2019 One can gather information regarding potential allergy by skin test and serum-specific IgE determinations, but definitive information is not available. A 23-year-old female presented with classical features of an immediate hypersensitivity reaction after contact with papaya. These antibodies cause your body to exhibit certain symptoms in an attempt to flush out the offending protein. During an allergic reaction, the body perceives these substances as a threat and histamine is released as a response, thus triggering the symptoms of an allergic reaction. Clinical cross-reactivity varies. We report a case of systemic contact dermatitis to raw cashew nuts, an atypical and unexpected ingredient flavoring an imported pesto sauce. However, there is strong cross-reactivity between cashew and pistachio. A cross-reactivity allergy is present when the antibodies against a specific allergen are also capable of identifying other aller-gens from other allergen sources and may thus induce an allergic reaction to those allergens as well. On the other hand, pistachio and cashew, as you know, demonstrate a great deal of cross-reactivity based on in vitro studies. In some of these, patients have also shown clinical reactivity to pistachio or cashew (5, 6). Allergy 2002; 57 Supplement, 73:85-105. There is a panallergen found in celery, carrot, apple, peanut, paprika, anise, fennel, coriander, and cumin that demonstrates cross-reactivity with mango. Some patients who react to mango have demonstrable cross-reactivity to pistachio or cashew, and others do not. Answer: A patient ate papaya and cashews and developed a delayed contact dermatitis. Toxicology 1994; 93(1):77-83. By continuing to browse this site, you are agreeing to our use of cookies. The exact incidence of mango allergy is unknown, but clearly reactions to this fruit occur far less frequently than... 2. Should a patient with proven allergy to cashew and pistachio always be told to avoid mango or should a separate evaluation for mango allergy be carried out on a case by case basis? If you are allergic to papain, avoid eating papaya or taking products that contain papaya. Many individuals with fruit allergy are sensitized to pollen or latex. Skin-specific IgE to papaya extracts was positive. Hegde VL, et al. Cross-reactions are frequently seen be-tween certain pollen types and foods. Question Posted 5/2/2012: American Academy of Allergy Asthma & Immunology, Cross-reactivity between papaya, mango and cashew, Allergist / Immunologists: Specialized Skills. Mango contains a number of different allergens which are found in many other foods besides pistachio and cashew. zucchini) that cross-reacts with a plant (ex.