(28-C (3) Outline a detailed mechanism for the acid catalyzed hydration of 2-methyl-2-butene and name the major product according to the IUPAC rules. Formula of chloroacetic acid is \(ClCH_2COOH\) Here, H atom is replaced by highly electron withdrawing Cl atom. 2-Chloroacetic acid is more acidic than acetic acid. So, chloroacetic acid is stronger than acetic acid. Acidic substances are substances that are capable of dissociating in solution to form a solution of protons and an anion. Chloroacetic acid is also used in the production of phenoxy herbicides by etherification with chlorophenols. Why? In this way 2-methyl-4-chlorophenoxyacetic acid (MCPA), 2,4-dichlorophenoxyacetic acid, and 2,4,5-trichlorophenoxyacetic acid (2,4,5-T) are produced. Thus fluoro acetic acid is more acidic than chloro acetic acid. 1 eq HI CH H3C-c-O-CH CHâ‚‚ I think this is the main reason of the acidicity difference, since the pKa's are similar (comparing glycine and chloroacetic acid). Hence Cl > Br in terms of electron withdrawing effect (-I effect) Once a proton is lost chloroacetate and bromoacetate are formed So, the negative charge density on O atom reduced and corresponding conjugate base is stabilised.. Thus, the acid strength of the acid increases. going down the group electronegativity decreases. Fluroacetic acid is more acedic than chloroacetic acid. Chloroacetic acid is stronger acid than bromoacetic acid. Inductive effect is responsible for the acidity of chloroacetic acid . Hence both the conditions make chloroacetic acid more acidic than acetic acid. Electron withdrawing atoms or groups at alpha carbon atom increases stability of the carboxylate anion by dispersing the charge.Hence acidic nature also increases. The correct order of increasing acidic strength is Ethanol . Thus, the acid strength of the acid increases. (5) Propose a detailed mechanism for the following reaction. Phenol Acetic acid Chloroacetic acid. It is the precursor to the herbicide glyphosate and dimethoate. Hence both the conditions make chloroacetic acid more acidic than acetic acid. Hence Cl is more electronegative than Br. Phenol is more acidic than ethanol because in phenol, the phenoxide ion obtained on deprotonation is stabilized by resonance which is not possible in case on ethanol. Update: glycine is amphoteric: it can either act as a base or an acid. So now the H+ atom can easily come out and the stability of the carboxylate ion has also increased. So now the H+ atom can easily come out and the stability of the carboxylate ion has also increased. Glycine hydrochloride is the amino acid glycine adsorving a molecule of Hydrochloric acid, wich is a strong acid. Define the concept of the inductive effect. The stronger the ewg (electron withdrawing group), the more acidic the compound.